Pioneer in ozonized glycerin Mediplus Pharma Inc.
Mediplus Pharma is the pioneer behind Ozonated Glycerin (OG), a proprietary ingredient developed through more than 50 years of research and technological innovation. Our OG maintains exceptional stability even at room temperature. In 2022, we advanced our work further by discovering a new OG-related compound and successfully obtaining a patent.
OG was registered as a cosmetic ingredient in 2004 and has since been widely used in skincare formulations. In 2010, its application expanded to oral-care cosmetics. In 2022, we established a dedicated production facility in Saitama Prefecture, enabling high-quality, large-scale manufacturing.
Our mission extends beyond human wellbeing. We are committed to improving the quality of life for animals as well, offering OG-based skincare and oral-care products that can complement pharmaceuticals and clinical treatments. OG exhibits strong affinity with skin, oral tissue, scalp, fur, and mucous membranes, enabling the development of gentle yet highly functional formulations.
We supply both OG raw materials and proprietary finished products to companies in Japan and abroad, and a growing number of partners are evaluating its adoption.
Pioneer in ozonized glycerin Mediplus Pharma Inc.
Mediplus Pharma is the pioneer behind Ozonated Glycerin (OG), a proprietary ingredient developed through more than 50 years of research and technological innovation. Our OG maintains exceptional stability even at room temperature.
In 2022, we advanced our work further by discovering a new OG-related compound and successfully obtaining a patent.
OG was registered as a cosmetic ingredient in 2004 and has since been widely used in skincare formulations. In 2010, its application expanded to oral-care cosmetics. In 2022, we established a dedicated production facility in Saitama Prefecture, enabling high-quality, large-scale manufacturing.
Our mission extends beyond human wellbeing. We are committed to improving the quality of life for animals as well, offering OG-based skincare and oral-care products that can complement pharmaceuticals and clinical treatments.
OG exhibits strong affinity with skin, oral tissue, scalp, fur, and mucous membranes, enabling the development of gentle yet highly functional formulations.
We supply both OG raw materials and proprietary finished products to companies in Japan and abroad, and a growing number of partners are evaluating its adoption.







