Profile

Company Profile

Company name
Mediplus Pharma, Inc.
Date of incorporation
March 1973 (former company name: VMC, Inc.)
Representative Director
KENJI ITO
Stated capital
93 million yen
Business activities
Development, manufacturing and marketing of pharmaceuticals, quasi-pharmaceutical products, and cosmetics
Location of business
Headquarters (with Radical Research Center)
5th Floor, Ebisu MF Building, 4-6-1, Ebisu, Shibuya-ku, Tokyo 150-0013 Japan
Saitama Factory
1392-10, Oaza Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806 Japan
Affiliated companies
Laugh Line Holdings, Inc.
Mediplus, Inc
Mediplus Research Institute, Inc
Mediplus International, Inc.
MEDIPLUS CO., LTD.（美楽思股份有限公司）
Affiliated Organizations
Japan Medical & Environmental Ozone Society
Japan Ozone Medical Society
Redox R&D Strategy Committee
RSPO (Roundtable on Sustainable Palm Oil)
Tokyo Cosmetic Industry Association
Tokyo Chamber of Commerce and Industry
Japan Cosmetic Certification Association
Japan Pet Products Manufacturers Association

Company History

March 1973
- Was established by Hirokazu Shiota
1994
- Since 1994, have implemented the private sector and government exchange joint research with the Forestry and Forest Products Research Institute of the Ministry of Agriculture, Forestry and Fisheries of Japan
1999
- For three years beginning 1999, had involved in the Livestock Industry’s Environmental Improvement Organization (LEIO)’s project titled
  “Development of Odor Prevention System Using Ozone Water”
2001
- For five years beginning 2001, had involved in the biomass project of the Ministry of Agriculture, Forestry and Fisheries of Japan titled
  “Development of Ozone Reactor for Pretreatment Processes on Enzymatic Saccharification of Wood Resources such as Waste Wood and Low-Grade Wastepaper”
October 2001
- Decided to become an entity certified under the Act for Facilitating Creation Activities of Small and Medium-sized Enterprises in Tokyo “Technology Development and Commercialization of Deodorizing System Using Direct Electrolysis Technology for Generating Ozone Water”
September 2004
- Decided to become an entity certified under the Act to Conduct Business Innovation of Small and Medium-sized Enterprises
- Registered ozonated glycerin as cosmetic raw material and launched skin cosmetics
December 2010
- Obtained patents for ozone gel both in Japan and the United States
April 2013
- Registered ozonated glycerin as oral cosmetics and launched oral cosmetics
April 2017
- The project titled “Development of Oral Hygiene Instruments for Dogs to Inhibit Oral Bacterial Growth and Improve Periodontal Disease” was adopted as the New Industry Creation Research Project of the Chugoku Industrial Innovation Center.
June 2018
- “Development of New Drugs for Bovine Mastitis Using Ozone Gel,” a project intended to obtain approval for animal drugs, was adopted as the project of Japan Science and Technology Agency (JST).
March 2019
- Concluded a comprehensive agent agreement with Sumitomo Corporation in the fields of animal drugs and miscellaneous goods.
July 2020
- 「Therapeutic effects of ozone ointment on sole ulcer of dairy cow」received the award from the chairman at National Agricultural Insurance Association.
February 2021
- Joined The Roundtable on Sustainable Palm Oil (RSPO), an international non-profit organization.
May 2021
- Launched fibonacci, a skincare brand for aging spots that compounds the original ingredient.
March 2023
- We incorporated our patented stabilized ozonized glycerin into the flagship product “Mediplus Gel” of our group company, Mediplus Co., Ltd.
December 2024
- We launched the dental oral cosmetic product “OG Paste,” made with our ozonized glycerin formulation.
January 2025
- We launched the veterinary oral cosmetic product “OG Gel,” made with our ozonized glycerin formulation.

Access

Headquarters (with Radical Research Center)
5th Floor, Ebisu MF Building, 4-6-1, Ebisu, Shibuya-ku, Tokyo 150-0013 Japan

Saitama Factory
1392-10, Oaza Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806 Japan

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