Entries by Mediplus Pharma

New ways to reduce facial age spots. Japanese Pharmaceutical R&D company Mediplus Pharma found the new ability of “High performance Glycerin” Effective in 92% of people after 8 weeks of continuous use.

2022-01-12 in , /by

FOR IMMEDIATE RELEASE Mediplus Pharma, Inc. (CEO: Kenji Ito, Head Office: Shibuya-ku, Tokyo,JAPAN) confirmed that cosmetics containing its patented ingredient, high performance ozonized glycerin, have the effect of reducing melanin (age spots) in the epidermis, and filed a new application patent which claimed melanin decomposition.

The Effect of Ozone Gel on Bone Matrix Production by Human Osteosarcoma Cell Line Saos-2

2018-04-20 in , /by

Pao-Li Wang1)*, Yoichi Tachi2)*, Kazuya Masuno1), Nobutaka Okusa3) and Yasuhiro Imamura4)1) Department of Innovation in Dental Education, Osaka Dental University, Osaka, Japan2) Laboratory of Nutritional Physiology, Tokyo Kasei University, Tokyo, Japan3) Department of Forensic Dentistry, Osaka Dental University, Osaka, Japan4) Department of Dental Pharmacology, Matsumoto Dental University, Shiojiri, Japan(Accepted for publication, April 20, 2018) Abstract Ozone is currently being considered […]

The Effect of Ozone on Collagen Type-1 and Inflammatory Cytokine Production in Human Gingival Fibroblasts

2015-05-10 in , , /by

Yoshimasa Makita1, Yasuhiro Imamura2, Kazuya Masuno3, Isao Tamura4, Shin-ichi Fujiwara1, Gotaro Shiota5, Akihiko Shiba6 and Pao-Li Wang7* 1Department of Chemistry, Osaka Dental University, Osaka, Japan2Department of Pharmacology, Matsumoto Dental University, Nagano, Japan3Department of Innovation in Dental Education, Osaka Dental University, Osaka, Japan4Department of Oral Anatomy, Osaka Dental University, Osaka, Japan5VMC Co., Ltd., Tokyo, Japan (currently Mediplas Pharmaceuticals)6Department of Prosthodontics, Faculty […]

Use of Ozone Gel in Various Fields Including Atopic Dermatitis and Its Future Application in Dentistry

2013-10-29 in , /by

Background and Purpose: In our country, it is estimated that approximately one in two people suffers from some form of allergy, with atopic dermatitis affecting about 10% of the population. Research into allergic diseases is gradually progressing, yet there are no complete preventive or curative treatments available. Current treatment primarily involves long-term symptomatic therapy through environmental management and pharmacotherapy with […]

The 36th Japanese Nursing Association Compendium: “Deodorization effects of ozone products against unpleasant cancer odor.”

2005-11-24 in , /by

Abstract: The last stage of a human life is a crucial period for people and their family. Various approaches are being used to study the way people want to spend their last moments, including palliative care. In this study, we succeeded in drastically reducing the unpleasant cancer odor of a patient who had long been bothered by it by using […]