Glutathione(GSH)

It is a compound (tripeptide) of multiple amino acids and is composed of three amino acids: glutamic acid, cysteine, and glycine. It is present in almost all cells in the body and has the function of protecting cells from reactive oxygen species. In Japan, it is positioned as a pharmaceutical product. It is considered useful for maintaining health and beauty.

Oxidation

Oxidation is a chemical reaction in which the target substance loses an electron. Specifically, it is a chemical reaction in which oxygen is compounded with a substance or a substance is deprived of hydrogen. Typical examples include rusting of metals, burning of paper and wood, and discoloration of apples. Since organic dyes become colorless by oxidation, oxidants are used as bleaching agents.

Antioxidant(Antioxidation)

Antioxidants(Antioxidations) inhibit the body from oxidizing, which is called antioxidant, antioxidant capacity, or antioxidant action. They inhibit the action of reactive oxygen species (ROS) to prevent the body from being affected by oxidation in various ways.

Hormesis

A phenomenon in which a substance is harmful when used in high concentrations or in large quantities, but is beneficial to the body when used in low concentrations or in small quantities. For example, exposure to large amounts of ultraviolet rays can cause skin cancer, but small amounts of ultraviolet rays are necessary for the body to produce active vitamin D. The word hormesis, like the word “hormone,” comes from the ancient Greek word “hormáein” (to set in motion, to spur, to urge).

SID(Society Investigate Dermatology)

The world prominent scientific research organization, which is composed of scientists in skin health and disease. The headquarters locate in Cleveland, Ohio, U.S.A, consists of members representing 32 countries. The annual convention is thought as the world’s highest-level conference in fundamental research of dermatology. The journals published regularly are highly prestigious, with the 5th highest Impact Factor in Dermatology section for the year 2021.

Homeostasis

The word is derived from ὅμοιοστάσις (means ‘identical state’) in Greek. It’s physiological functions that always keep in stable condition, regardless of environmental changes inside an organism and outside, consequently quite essential for living things. Homeostasis works as an overall organism function such as controlling vital warmth and blood pressure, eliminating pathogen and viruses, repairing injury and so on.

Cytokine

Cylokine is an important regulator of inflammation, a general term for small molecule proteins secreted by cells. Also called bioactive proteins. They are produced in response to pathogens such as viruses that invade the body and stimulate, mobilize, and proliferate immune functions.

messengerRNA, messenger Ribonucleic acid

mRNA(messenger RNA, messenger Ribonucleic acid) Also called transmissible RNA (ribonucleic acid). It is a single-stranded RNA that is transcribed from DNA in the process of protein synthesis in cells. The genetic information contained in DNA is read by ribosomes in the cell and translated into protein. After a certain period of time, the RNA is degraded by the action of RNA degrading enzymes.

NF-E2-related factor 2

NH-E2-related factor 2 is the body maintains homeostasis by regulating the balance between oxidation and anti-oxidation, and the Nrf2 transcription factor is one of the factors responsible for this maintenance function. It has been shown that it is activated by substances that oxidize and attack biological macromolecules such as DNA and proteins to enhance transcription of target genes and protect cells in various aspects.

Homeostasis

The word is derived from ὅμοιοστάσις (means ‘identical state’) in Greek. It’s physiological functions that always keep in stable condition, regardless of environmental changes inside an organism and outside, consequently quite essential for living things. Homeostasis works as an overall organism function such as controlling vital warmth and blood pressure, eliminating pathogen and viruses, repairing injury and so on.