NH-E2-related factor 2 is the body maintains homeostasis by regulating the balance between oxidation and anti-oxidation, and the Nrf2 transcription factor is one of the factors responsible for this maintenance function. It has been shown that it is activated by substances that oxidize and attack biological macromolecules such as DNA and proteins to enhance transcription of target genes and protect cells in various aspects.
The word is derived from ὅμοιοστάσις (means ‘identical state’) in Greek. It’s physiological functions that always keep in stable condition, regardless of environmental changes inside an organism and outside, consequently quite essential for living things. Homeostasis works as an overall organism function such as controlling vital warmth and blood pressure, eliminating pathogen and viruses, repairing injury and so on.
The world prominent scientific research organization, which is composed of scientists in skin health and disease. The headquarters locate in Cleveland, Ohio, U.S.A, consists of members representing 32 countries. The annual convention is thought as the world’s highest-level conference in fundamental research of dermatology. The journals published regularly are highly prestigious, with the 5th highest Impact Factor in Dermatology section for the year 2021.