Dermoscopy
Dermoscopy is the examination of pigmented lesions on the skin, such as moles and tumors, using a lighted magnifying glass called a dermoscope.
It provides much more accurate information than that seen with the naked eye.
Filaggrin
/in Glossary /by Mediplus PharmaFilaggrin is a crucial structural protein in the epidermis, the outermost layer of the skin. It is an essential protein for maintaining the morphology and function of keratinocytes in the barrier function of the stratum corneum. Dysfunction or deficiency of filaggrin is associated with the development of atopic dermatitis, and a lack of filaggrin can also cause dry skin.
Involucrin
/in Glossary /by Mediplus PharmaInvolucrin is a structural protein predominantly found in the epidermis of the skin. During the formation of the stratum corneum, the outermost layer of the skin, it plays a role in strengthening the cell membrane and enhancing the skin’s protective functions.
NAD(P)H: Quinone
/in Glossary /by Mediplus PharmaNAD(P)H: Quinone Oxidoreductase 1 (NQO1) is an enzyme that plays a crucial role in cellular defense mechanisms by reducing quinones to hydroquinones. This action helps protect cells from oxidative stress and contributes to various protective functions such as detoxification, anti-inflammatory regulation, and anticancer effects within the body.
Hem Oxygenase-1
/in Glossary /by Mediplus PharmaHeme Oxygenase-1 (HO-1) is a type of enzyme within the heme oxygenase family, specifically activated under stress conditions. HO-1 catalyzes the degradation of heme within cells, resulting in the production of biliverdin, iron ions, and carbon monoxide (CO). This enzyme exhibits antioxidant and anti-inflammatory properties and plays a crucial role in protecting cells from stress and damage.
In vitro
/in Glossary /by Mediplus PharmaIn vitro is an artificially constructed condition or environment in which human or animal tissues are used in a test tube or culture medium to reproduce an environment similar to that inside the body, for example, in biological experiments. It is also used in the sense of such tests.
Hydroxy group
/in Glossary /by Mediplus PharmaA hydroxy group is a functional group with the chemical formula -OH in organic chemistry.
Precursor
/in Glossary /by Mediplus PharmaA precursor, or precursor substance, in chemistry, is a substance in a stage before it is formed.
Spinous layer
/in Glossary /by Mediplus PharmaThe spinous layer is the thickest layer of the epidermis. The layer of the spinous layer contains lymphatic drainage and receives oxygen and nutrients from the dermis, which lies beneath the epidermis.
Granular layer
/in Glossary /by Mediplus PharmaThe granular layer is the second layer from the top of the epidermis and it is one to several very thin layers.