The world’s leading academic journal on cosmetic dermatology「Journal of Cosmetic Dermatology」has accepted Mediplus Pharma’s article ” Ozonized glycerin (OG)-based cosmetic products lighten age spots on human facial skin“”

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Mediplus Pharma is presenting posters at Society for Investigative Dermatology(SID)annual meeting 2022

Mediplus Pharma, Inc. (CEO: Kenji Ito, Head Office: Shibuya-ku, Tokyo,JAPAN) made a scientific presentation at the annual meeting of the Society for Investigative Dermatology (May 18-21, 2022, Portland, USA), which is considered the world’s highest-level society in dermatological research.

Title:Novel glycerin compounds improve skin health

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New ways to reduce facial age spots. Japanese Pharmaceutical R&D company Mediplus Pharma found the new ability of “High performance Glycerin” Effective in 92% of people after 8 weeks of continuous use.


Mediplus Pharma, Inc. (CEO: Kenji Ito, Head Office: Shibuya-ku, Tokyo,JAPAN) confirmed that cosmetics containing its patented ingredient, high performance ozonized glycerin, have the effect of reducing melanin (age spots) in the epidermis, and filed a new application patent which claimed melanin decomposition.

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The 36th Japanese Nursing Association Compendium: “Deodorization effects of ozone products against unpleasant cancer odor.”


The last stage of a human life is a crucial period for people and their family. Various approaches are being used to study the way people want to spend their last moments, including palliative care. In this study, we succeeded in drastically reducing the unpleasant cancer odor of a patient who had long been bothered by it by using ozone gel and ozone water. The treatment also cleansed the surface of the ulcer, suggesting that ozone gel might positively contribute to endstage medicine. This treatment suppressed the unpleasant odor and cleansed the patient’s body in her last stage, indicating that ozone gel might help people to spend their twilight years with dignity. With the hope of helping such patients, we intend to accelerate the development of medical products containing ozone gel and make them accessible as soon as possible. This case report summarizes an article presented at the 36th Japanese Nursing Association Compendium–General Nursing published by the Japanese Nursing Association on November 24, 2005.

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Investigation of Bactericidal and Fungicidal Effects of Stabilized Ozone Gel

Mediplus Pharma, Inc. (Formerly VMC Corporation) Gotaro Shiota
Yoshiaki Maruyama, Kikumi Suzuki
Showa University School of Dentistry, Department of Prosthodontics, Akihiko Shiba
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Shiba Kiyoko, Okamura Noboru,
Chida Toshio
Division of Laboratory Medicine, Chiba University Hospital, Asako Kimura Read more